Results

    

The activities are aiming to developing technologies for synthesis and thermo-mechanical processing of the new TiZrNbTa alloy and its surface functionalisation by coating with  low wear multicomponent carbonitrides (TiZrCN, ZrNbCN, TiNbAgCN) and doped HAP osseoconductive coatings (SiC-HAP, SiC-Ag-HAP).

 
Activities carried out by consortium partners

    2017

  1. Experimental model for bioalloy synthesis, tests procedures - Technical specifications (R&D)
  2. Experimental development of TiNbZrTa alloy synthesis technology (R&D)
  3. Design and development of thermo-mechanical processing-TM-P of TiNbZrTa alloy (R&D)
  4. Alloy synthesis and TM-P experiments for test lot 1 (R&D)
  5. Complex characterization of the as cast and S-TM-P test lot-1 samples: composition, crystallographic structure, corrosion resistance in SBF, tribocorosion tests  (R&D, INOE)
  6. Preliminary experiments on low wear & doped HAP-osseoconductive coatings, test procedures - Technical specifications (INOE)
  7. Design and experimental development of coating technologies for low wear and doped HAP-osseoconductive coatings
  8. Surface functionalization of test lot 1 by low wear and doped HAP-osseoconductive coatings
  9. Characterization of low wear and doped HAP-osseoconductive coatings - part I: crystallographic structure

 

 2018

  1. Processed bioalloy test lot 2; validation of S-TM-P lab technologies
  2. Characterization of the bioalloy test lot 2
  3. Surface functionalization of test lot 2 bioalloy; validation of SF-PVD lab technologies
  4. Complex caracterization of the coated test lot 2 alloy
  5. In vitro biological testing of uncoated and coated alloy
  6. Fabrication of the implants for in-vivo tests (uncoated and coated)
  7. In-vivo testing of uncoated and coated alloy
  8. Exploitation of the project results
  9. Protection of RTD results
  10. Dissemination of the project results
Delivered items

    2017 

  1. Specifications for total arthroplasty implant biomaterial
  2. Report on requirements for alloy samples, characterization and testing methods for as cast and processed alloy, technologies issues
  3. Report on requirements for coated samples (quantity, dimension, characteristics), characterization and testing methods for coatings
  4. Experimental model for alloy synthesis and for alloy thermo-mechanical processing
  5. Test lot 1 of thermo-mechanical processed TiNbZrTa alloy
  6. Characterization reports of cast and thermo-mechanically processed bioalloy
  7. Report of corrosion and tribo-corrosion tests of TiNbZrTa alloy
  8.  Test lot 1 of thermo-mechanically alloy with appropriate properties for implant material
  9. Documentation for coating technology
  10. Experimental models: low wear and doped HAP coatings
  11. Coated alloy test lot 1
  12. Characterization report on crystalline structure of coatings deposited on lot 1 bioalloy
Annual report

2018


  • Validation by in-vitro and in-vivo tests of the technological chain (lab. S-TM-P and SF-PVD technologies) for the new TA implant biomaterial manufacturing.
  • Test lot 2 of Ti-10Nb-10Zr-5Ta using S-TM-P technologies
  • Chemical and structural characterization of Test lot 2 of Ti-10Nb-10Zr-5Ta bioalloy
  • Coating of the test lot 2 bioalloy, using the lab SF-PVD technologies for d-HAP & L3 coatings.
  • d-HAP & L3  coatings for structure (XRD), composition (EDS, Auger electron spectrocopy), surface energy and hydrophobicity, corrosion (EIS) and tribo-corrosion in SBF
  • In vitro tests on cell viability and proliferation, adhesion and osteoblast morphology, cell differentiation, matrix mineralization on: uncoated and coated (osseoconductive d-HAP, and low friction L3) samples.
  • Fabrication of implants for in-vivo tests using the S-TM-P bioalloy.
  • Deposition of coatings on bioalloy samples for surface functionalization.
  • Validated S-TM-P lab-technology for Ti based bioalloy
  • Validated PVD-SF lab-technology for surface functionalized bioalloy.
  • In-vivo testing of uncoated and HAP coated alloy
  • Patent application
  • Results communications and publication
  • Annual report
  • Final report

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